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Table 3 Associations between BBD, parity, and timing of first birth relative to BBD diagnosis and mammographic breast density (percent MBD, dense area, and non-dense area), EDMD

From: Benign breast disease and changes in mammographic breast density

   Adjusted for Age, Race, and BMI
Variables N Estimate Standard error p-value 95% CI
Percent density, first available mammogram
 No BBD, nulliparous 108 3.07 1.79 0.09 −0.44, 6.58
 No BBD, parous 440 Ref
 BBD, nulliparous 37 7.25 2.43 < 0.01 2.50, 12.01
 BBD before first birth 25 7.84 2.98 0.01 2.01, 13.68
 BBD after first birth 53 −0.22 2.40 0.93 −4.92, 4.49
Percent density, last available mammogram*
 No BBD, nulliparous 68 2.76 1.88 0.14 −0.92, 6.45
 No BBD, parous 262 Ref
 BBD, nulliparous 15 4.44 3.94 0.26 −3.28, 12.16
 BBD before first birth 19 10.61 3.80 0.01 3.17, 18.05
 BBD after first birth 31 0.56 3.13 0.86 −5.57, 6.70
Dense area, first available mammogram
 No BBD, nulliparous 108 −1.77 2.36 0.45 −6.40, 2.86
 No BBD, parous 440 Ref
 BBD, nulliparous 37 8.26 3.80 0.03 0.82, 15.70
 BBD before first birth 25 −0.16 3.53 0.96 −7.09, 6.76
 BBD after first birth 53 0.19 3.18 0.95 −6.04, 6.41
Dense area, last available mammogram*
 No BBD, nulliparous 68 1.53 2.96 0.61 −4.27, 7.33
 No BBD, parous 262 Ref
 BBD, nulliparous 15 6.11 5.50 0.27 −4.66, 16.88
 BBD before first birth 19 1.43 3.79 0.71 −6.00, 8.85
 BBD after first birth 31 2.12 4.74 0.66 −7.18, 11.41
Non-dense area, first available mammogram
 No BBD, nulliparous 108 −10.85 6.69 0.11 −23.95, 2.26
 No BBD, parous 440 Ref
 BBD, nulliparous 37 −13.20 7.98 0.10 −28.83, 2.44
 BBD before first birth 25 −17.07 7.44 0.02 −31.66, −2.49
 BBD after first birth 53 1.65 8.16 0.84 −14.35, 17.65
Non-dense area, last available mammogram*
 No BBD, nulliparous 68 −4.17 7.42 0.57 −18.70, 10.36
 No BBD, parous 262 Ref
 BBD, nulliparous 15 −11.27 13.53 0.40 −37.80, 15.25
 BBD before first birth 19 −20.95 7.10 < 0.01 −34.87, −7.04
 BBD after first birth 31 5.93 13.61 0.66 −20.74, 32.60
  1. *Only among women with at least 2 available mammograms