Table 3 Associations between BBD, parity, and timing of first birth relative to BBD diagnosis and mammographic breast density (percent MBD, dense area, and non-dense area), EDMD
From: Benign breast disease and changes in mammographic breast density
Adjusted for Age, Race, and BMI | |||||
|---|---|---|---|---|---|
Variables | N | Estimate | Standard error | p-value | 95% CI |
Percent density, first available mammogram | |||||
No BBD, nulliparous | 108 | 3.07 | 1.79 | 0.09 | −0.44, 6.58 |
No BBD, parous | 440 | Ref | – | – | – |
BBD, nulliparous | 37 | 7.25 | 2.43 | < 0.01 | 2.50, 12.01 |
BBD before first birth | 25 | 7.84 | 2.98 | 0.01 | 2.01, 13.68 |
BBD after first birth | 53 | −0.22 | 2.40 | 0.93 | −4.92, 4.49 |
Percent density, last available mammogram* | |||||
No BBD, nulliparous | 68 | 2.76 | 1.88 | 0.14 | −0.92, 6.45 |
No BBD, parous | 262 | Ref | – | – | – |
BBD, nulliparous | 15 | 4.44 | 3.94 | 0.26 | −3.28, 12.16 |
BBD before first birth | 19 | 10.61 | 3.80 | 0.01 | 3.17, 18.05 |
BBD after first birth | 31 | 0.56 | 3.13 | 0.86 | −5.57, 6.70 |
Dense area, first available mammogram | |||||
No BBD, nulliparous | 108 | −1.77 | 2.36 | 0.45 | −6.40, 2.86 |
No BBD, parous | 440 | Ref | – | – | – |
BBD, nulliparous | 37 | 8.26 | 3.80 | 0.03 | 0.82, 15.70 |
BBD before first birth | 25 | −0.16 | 3.53 | 0.96 | −7.09, 6.76 |
BBD after first birth | 53 | 0.19 | 3.18 | 0.95 | −6.04, 6.41 |
Dense area, last available mammogram* | |||||
No BBD, nulliparous | 68 | 1.53 | 2.96 | 0.61 | −4.27, 7.33 |
No BBD, parous | 262 | Ref | – | – | – |
BBD, nulliparous | 15 | 6.11 | 5.50 | 0.27 | −4.66, 16.88 |
BBD before first birth | 19 | 1.43 | 3.79 | 0.71 | −6.00, 8.85 |
BBD after first birth | 31 | 2.12 | 4.74 | 0.66 | −7.18, 11.41 |
Non-dense area, first available mammogram | |||||
No BBD, nulliparous | 108 | −10.85 | 6.69 | 0.11 | −23.95, 2.26 |
No BBD, parous | 440 | Ref | – | – | – |
BBD, nulliparous | 37 | −13.20 | 7.98 | 0.10 | −28.83, 2.44 |
BBD before first birth | 25 | −17.07 | 7.44 | 0.02 | −31.66, −2.49 |
BBD after first birth | 53 | 1.65 | 8.16 | 0.84 | −14.35, 17.65 |
Non-dense area, last available mammogram* | |||||
No BBD, nulliparous | 68 | −4.17 | 7.42 | 0.57 | −18.70, 10.36 |
No BBD, parous | 262 | Ref | – | – | – |
BBD, nulliparous | 15 | −11.27 | 13.53 | 0.40 | −37.80, 15.25 |
BBD before first birth | 19 | −20.95 | 7.10 | < 0.01 | −34.87, −7.04 |
BBD after first birth | 31 | 5.93 | 13.61 | 0.66 | −20.74, 32.60 |