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Table 1 Patients, tumor, and systemic therapy characteristics

From: IOERT versus external beam electrons for boost radiotherapy in stage I/II breast cancer: 10-year results of a phase III randomized study

 

IOERT boost arm

EBRT boost arm

p value

Women in each arm

125 (51%)

110 (49%)

 

Median age (range)

56.3 years (29–75)

56.2 years (34–75)

0.96**

Menopausal status

0.81*

 Pre

37 (30%)

31 (28%)

 

 Post

88 (70%)

79 (72%)

 

Disease laterality

0.73*

 Right breast

54 (43%)

50 (45%)

 

 Left breast

71 (57%)

60 (55%)

 

Histology

0.46*

 IDC

61 (49%)

59 (54%)

 

 ILC

17 (14%)

11 (10%)

 

 DCIS

3 (1.4%)

3 (2.6%)

 

 IDC+DCIS

32 (26%)

24 (22%)

 

 Medullary

6 (5%)

4 (3.5%)

 

 ILC+ILCS

5 (4%)

5 (4.4%)

 

 Missing

1 (0.6%)

4 (3.5%)

 

Pathologic T stage

0.38*

 pT1

96 (77%)

79 (72%)

 

 pT2

28 (22%)

22 (20%)

 

 pT3–pT4

1 (1%)

1 (1%)

 

 Missing

0

8 (7%)

 

Pathologic N stage

0.55*

 pN0

82 (65%)

68 (62%)

 

 pN1

38 (30%)

32 (29%)

 

 pN2

2 (2.1%)

1 (1%)

 

 pN3

1 (0.8%)

1 (1%)

 

 Missing

2 (2.1%)

8 (7%)

 

Adjuvant chemotherapy

0.61*

 Yes

37 (30%)

36 (33%)

 

 Not

85 (68%)

64 (58%)

 

 Missing

3 (2%)

10 (9%)

 

Hormone therapy

0.66*

 Yes

105 (84%)

90 (81%)

 

 Not

19 (15%)

12 (11%)

 

 Missing

1 (1%)

8 (8%)

 
  1. Abbreviations: IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; DCIS, ductal carcinoma in situ
  2. **Mann-Whitney test
  3. *Chi-square test