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Fig. 1 | Breast Cancer Research

Fig. 1

From: Inhibition of stromal biglycan promotes normalization of the tumor microenvironment and enhances chemotherapeutic efficacy

Fig. 1

Biglycan is highly expressed in tumor stroma, associated with angiogenesis gene expression and prognosis of human breast cancer patients. a Comparison of biglycan mRNA expression was analyzed in normal mammary glands (n = 61) and breast cancer tissue (n = 389) using Oncomine. b Comparison of biglycan mRNA expression was analyzed in 14 patient-matched tumor epithelium and tumor-associated stroma specimens using Oncomine. c Kaplan-Meier analysis was used to assess breast cancer patients with high or low biglycan mRNA expression in distant metastasis-free survival (DMFS) using a Kaplan-Meier plotter tool. d Kaplan-Meier analysis was used to assess breast cancer patients with high or low biglycan protein expression in DMFS using a Kaplan-Meier plotter tool. e Correlation between BGN and PECAM1 expression using cBioPortal database. f Correlation between BGN and ANGPT2 expression using cBioPortal database

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