Breast adipose tissue macrophages (BATMs) have a stronger correlation with breast cancer survival than breast tumor stroma macrophages (BTSMs)

Table 4 BC survival analysis using a combination of the prognostic factors EP3 and BATMs

	OS%	p value	HR	95% CI	DFS%	p value	HR	95% CI
A.
EP3 high+BATM low	83.1				77.4
EP3 high+BATM high	70.0	0.059	2.128	0.973–4.658	66.7	0.326	1.437	0.697–2.962
EP3 low+BATM low	58.1	0.01*	1.511	1.102–2.070	60.5	0.028*	1.405	1.037–1.902
EP3 low+BATM high	35.0	0.000002*	1.756	1.391–2.217	60.0	0.000005*	1.922	1.453–2.544
B.
BATM high+EP3 high	70.0				66.7
BATM high+EP3 low	35.0	0.023*	1.647	1.070–2.536	60.0	0.004*	2.107	1.264–3.513
C.
BATM low+EP3 high	83.1				77.4
BATM low+EP3 low	58.1	0.01*	1.511	1.102–2.070	60.5	0.028*	1.405	1.037–1.902
D.
EP3 high+BATM low	83.1				77.4
EP3 high+BATM high	70.0	0.059	2.128	0.973–4.658	66.7	0.326	1.437	0.697–2.962
E.
EP3 low+BATM low	58.1				60.5
EP3 low+BATM high	35.0	0.007*	2.722	1.321–5.609	60.0	0.002*	4.049	1.665–9.847

BATMs breast adipose tissue macrophage, EP3 prostaglandin E receptor 3, OS overall survival, DFS disease-free survival, p p value, HR hazard ratio, CI confidence interval; *significant (p value < 0.05)

ISSN: 1465-542X