Fig. 1

BATMs and BTSMs distribution in BC. A strong correlation was found between the quantity of BATMs and BTSMs (r = 0.5, p = 2.98E−15) (e). The number of BATMs in patients aged older than 50 years was significantly higher than in patients younger than50 years (a, b, f). The quantity of BTSMs was significantly related to BC molecular type (p = 0.0003, g) and was significantly higher in TNBC than in luminal A-like BC (p = 0.0005, g) (c, d). Regarding only ER-status independent of the biological subtype, the quantity of BTSM in ER- patients was significantly higher than in ER+ patients (p = 0.002, h) (c, d). BTAMs, breast adipose tissue macrophages; BTSMs, breast tumor-stroma macrophages; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; LuA-like, luminal A-like; LuB-like, luminal B-like; TNBC, triple-negative breast cancer; HER2 Lu-like, HER2 amplified luminal-like; HER2 nonLu like, HER2 amplified non luminal-like