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Fig. 7 | Breast Cancer Research

Fig. 7

From: High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer

Fig. 7

Higher cancer cell IRF8 expression levels is associated with an increased infiltration of CD45+ HLA-DR+ cells. a Myeloid cell percentages were quantified as a percentage of total CD45+ cells. b MHC II expression on CD45+ CD66b tryptase CD68 cells. c Correlation between IRF8 protein expression and HLA-DRA evaluated using iTRAQ. d Immature (DCsign+) dendritic cells (iDC) and mature (LAMP+) dendritic cells (mDC) percentages were quantified as a percentage of CD45+ CD66b tryptase CD68 HLA-DR+ cells. e Frequency of macrophages expressing Ki67, IL10, or IDO. *p < 0.05

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