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Fig. 2 | Breast Cancer Research

Fig. 2

From: High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer

Fig. 2

Methylation of IRF8 in BC cell lines and samples. a Methylation of the IRF8 promoter was evaluated by methylation-specific PCR (MSP) in the BC cell lines MDA231 and MCF7 (M: methylated; U: unmethylated). b Expression of IRF8 evaluated by western blot in MDA231 and MCF7 cells. c Correlation of IRF8 promoter methylation and gene expression in BC samples. Data are from The MethHC database tool (http://methhc.mbc.nctu.edu.tw/). Gene expression value was obtained from RNA Seq RPKM (reads per kilobase per million mapped reads) values in TCGA Data Portal. Data shown in a and b are representative of two experiments performed

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