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Table 2 Patient characteristics (US group) according to tumor size estimation and discordance between US and histology

From: Magnetic resonance imaging and ultrasound for prediction of residual tumor size in early breast cancer within the ADAPT subtrials

  Overestimation
US – Histol. > 10 mm
Difference
US – Histol. ≤10 mm
Underestimation
US – Histol. > 10 mm
Unknown Total
Number of patients (% of total) 60 (10.20) 407 (69.22) 93 (15.82) 28 (4.76) 588 (100.00)
Age at initial visit [years]
 Mean 53.13 51.16 52.89 52.46 51.70
 SD 12.49 11.71 9.54 10.84 11.44
 Median 50.00 51.00 53.00 50.00 51.00
 Min 31.00 21.00 32.00 30.00 21.00
 Max 75.00 77.00 78.00 74.00 78.00
 N.d. 0 2 0 0 2
Central grade, N (%)
 1 0 (0.00) 8 (80.00) 2 (20.00) 0 (0.00) 10 (100.00)
 2 32 (13.60) 168 (71.19) 27 (11.44) 9 (3.81) 236 (100.00)
 3 28 (8.26) 228 (67.26) 64 (18.88) 19 (5.60) 339 (100.00)
 N.d. 0 (0.00) 3 (100.00) 0 (0.00) 0 (0.00) 3 (100.00)
Clinical baseline characteristics, N (%)
 cT
  1 15 (6.36) 196 (83.05) 14 (5.93) 11 (46.61) 236 (100.00)
  2 35 (11.11) 196 (62.22) 68 (21.59) 16 (5.08) 315 (100.00)
  3 7 (23.33) 12 (40.00) 10 (33.33) 1 (3.33) 30 (100.00)
  4 3 (42.86) 3 (42.86) 1 (14.29) 0 (0.00) 7 (100.00)
 cN
  0 33 (7.97) 304 (73.43) 58 (14.01) 19 (4.59) 414 (100.00)
  1 25 (16.23) 93 (60.39) 30 (19.48) 6 (3.90) 154 (100.00)
  2 2 (10.53) 9 (47.37) 5 (26.32) 3 (15.79) 19 (100.00)
  3 0 (0.00) 1 (100.00) 0 (0.00) 0 (0.00) 1 (100.00)
Menopausal status, N (%)
 Premenopausal 31 (10.99) 199 (70.57) 38 (13.48) 14 (4.96) 282 (100.00)
 Postmenopausal 28 (10.07) 189 (67.99) 49 (17.63) 12 (4.32) 278 (100.00)
 Unknown/unclear 1 (3.57) 19 (67.86) 6 (21.43) 2 (7.14) 28 (100.00)
BC subtype, N (%)
 HR+/HER2+ 28 (10.98) 187 (73.33) 31 (12.16) 9 (3.53) 255 (100.00)
 HR−/HER2− 26 (10.44) 166 (66.67) 45 (18.07) 12 (4.82) 249 (100.00)
 HR−/HER2+ 6 (7.14) 54 (64.29) 17 (20.24) 7 (8.33) 84 (100.00)
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