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Table 1 Patient characteristics (MRI group) according to tumor size estimation and discordance between MRI and histology

From: Magnetic resonance imaging and ultrasound for prediction of residual tumor size in early breast cancer within the ADAPT subtrials

  Overestimation
MRI – Histol. > 10 mm
Difference
MRI – Histol. ≤10 mm
Underestimation
MRI – Histol. > 10 mm
Unknown Total
Number of patients (% of total) 11 (4.44) 159 (64.11) 54 (21.77) 24 (9.68) 248 (100.00)
Age at initial visit [years]
 Mean 43.27 52.06 52.19 49.33 51.43
 SD 6.18 11.31 11.29 9.47 11.08
 Median 44.00 52.00 53.00 50.00 52.00
 Min 26.00 25.00 30.00 34.00 25.00
 Max 50.00 78.00 75.00 70.00 78.00
 N.d. 0 2 0 0 2
Central grade, N (%)
 1 0 (0.00) 4 (80.00) 1 (20.00) 0 (0.00) 5 (100.00)
 2 5 (4.49) 66 (65.35) 22 (21.78) 8 (7.92) 101 (100.00)
 3 6 (4.29) 88 (62.86) 30 (21.43) 16 (11.43) 140 (100.00)
 N.d. 0 (0.00) 1 (50.00) 1 (50.00) 0 (0.00) 2 (100.00)
Clinical baseline characteristics, N (%)
 cT
  1 5 (4.59) 80 (73.39) 19 (17.43) 5 (4.59) 109 (100.00)
  2 6 (4.72) 78 (61.42) 29 (22.83) 14 (11.02) 127 (100.00)
  3 0 (0.00) 1 (10.00) 5 (50.00) 4 (40.00) 10 (100.00)
  4 0 (0.00) 0 (0.00) 1 (50.00) 1 (50.00) 2 (100.00)
 cN
  0 6 (3.66) 121 (73.78) 30 (18.29) 7 (4.27) 164 (100.00)
  1 5 (6.85) 34 (46.58) 21 (28.77) 13 (17.81) 73 (100.00)
  2 0 (0.00) 4 (40.00) 3 (30.00) 3 (30.00) 10 (100.00)
  3 0 (0.00) 0 (0.00) 0 (0.00) 1 (100.00) 1 (100.00)
Menopausal status, N (%)
 Premenopausal 11 (9.24) 72 (60.50) 23 (19.84) 13 (10.92) 119 (100.00)
 Postmenopausal 0 (0.00) 80 (67.23) 28 (23.53) 11 (9.24) 119 (100.00)
 Unknown/unclear 0 (0.00) 7 (70.00) 3 (30.00) 0 (0.00) 10 (100.00)
BC subtype, N (%)
 HR+/HER2+ 5 (4.72) 66 (62.26) 30 (28.30) 5 (4.72) 106 (100.00)
 HR−/HER2− 6 (6.52) 62 (67.39) 13 (14.13) 11 (11.96) 92 (100.00)
 HR−/HER2+ 0 (0.00) 31 (62.00) 11 (22.00) 8 (16.00) 50 (100.00)
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