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Table 1 Morphological features of MCF10ADCIS orthotopic xenograft lesions

From: Multi-modal imaging of high-risk ductal carcinoma in situ of the breast using C2Am: a targeted cell death imaging agent

Cohort A B C
Time of tissue harvest post-implantation (weeks) 2 5 8
Number of fat pads injected (N) 4 6 10
Histologically confirmed DCIS/fat pads examined 2/4 6/6 10/10
Tissue architecture of DCIS lesions
 Solid 2/2 4/6 2/6
 Cribriform 0/2 3/6 2/6
Comedo 0/2 2/6 6/6
Mixed DCIS (at least two types/specimen) 0/2 4/6 2/6
Associated invasive carcinoma 0/2 2/6 4/6
  1. n = 10 mice, 18 lesions