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Table 5 Changes in infiltration levels of T lymphocyte (CD3+) and regulatory T lymphocytes (FOXP3+) over tumor progression

From: Regulatory T lymphocyte infiltration in metastatic breast cancer—an independent prognostic factor that changes with tumor progression

  

N

Low → high

High → low

Discordance (%)

P

CD3

Prim → Lnm

69

10

7

24,6

0,63

Lnm → Dm

14

1

2

21,4

1,0

Prim → Dm

26

1

3

15,4

0,63

FOXP3

Prim → Lnm

69

19

12

44,9

0,28

Lnm → Dm

14

4

4

57,1

1,0

Prim → Dm

26

5

8

50,0

0,58

  1. Abbreviations: N number of patients included in analysis, Prim primary tumor, Lnm lymph node metastasis, Dm distant metastasis. T lymphocytes (CD3) dichotomized into low (0 + 1 + 2) and high (3) infiltration. Regulatory T lymphocytes dichotomized into low (0) and high (1 + 2 + 3) infiltration. P value from McNemar’s test