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Table 5 Changes in infiltration levels of T lymphocyte (CD3+) and regulatory T lymphocytes (FOXP3+) over tumor progression

From: Regulatory T lymphocyte infiltration in metastatic breast cancer—an independent prognostic factor that changes with tumor progression

   N Low → high High → low Discordance (%) P
CD3 Prim → Lnm 69 10 7 24,6 0,63
Lnm → Dm 14 1 2 21,4 1,0
Prim → Dm 26 1 3 15,4 0,63
FOXP3 Prim → Lnm 69 19 12 44,9 0,28
Lnm → Dm 14 4 4 57,1 1,0
Prim → Dm 26 5 8 50,0 0,58
  1. Abbreviations: N number of patients included in analysis, Prim primary tumor, Lnm lymph node metastasis, Dm distant metastasis. T lymphocytes (CD3) dichotomized into low (0 + 1 + 2) and high (3) infiltration. Regulatory T lymphocytes dichotomized into low (0) and high (1 + 2 + 3) infiltration. P value from McNemar’s test