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Table 4 Correlation between T lymphocyte (CD3+) infiltration and Treg (FOXP3+) infiltration in primary tumors, lymph node metastases, and distant metastases

From: Regulatory T lymphocyte infiltration in metastatic breast cancer—an independent prognostic factor that changes with tumor progression

   CD3
Lnm
CD3
Dm
FOXP3
Prim
FOXP3
Lnm
FOXP3
Dm
CD3
Prim
R 0,22 0,12 0,54 0,23 -0,24
p 0,068 0,57 0,000 0,063 0,24
N 69 26 172 68 26
CD3
Lnm
R   -0,39 0,26 0,55 0,23
p   0,17 0,031 0,000 0,42
N   14 70 78 14
CD3
Dm
R    -0,074 -0,47 0,61
p    0,72 0,088 0,000
N    26 14 34
FOXP3
Prim
R     0,19 -0,18
p     0,12 0,37
N     69 26
FOXP3
Lnm
R      -0,35
p      0,22
N      14
  1. Abbreviations: R correlation coefficient, N number of patients included in analysis, Prim primary tumor, Lnm lymph node metastasis, Dm distant metastasis. Spearman correlati on, two-tailed P value. Bold indicates P value < 0.05