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Fig. 6 | Breast Cancer Research

Fig. 6

From: Identification of MFGE8 and KLK5/7 as mediators of breast tumorigenesis and resistance to COX-2 inhibition

Fig. 6

Identification of COX-2 associated genes contributing to COX-2 inhibitor resistance in TNBC cells. a MDA-MB-231 control and KO cell lines were treated with a dose rage of celecoxib for 4 days and subjected to cell viability test using SRB assay. IC50 values of control and each KO cells were indicated. b Celecoxib dose response curve in MDA-MB-231 control, LAMC2, KLK7, MFGE8, KLK5, and SLC2A1 KO cells. c MDA-MB-231 control, LAMC2, MFGE8, KLK5, and SLC2A1 KO cells were treated with 50 μM celecoxib for 4 days and then subjected to Prestoblue cell viability assay. Percentage of living cells after celecoxib treatment was calculated

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