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Fig. 2 | Breast Cancer Research

Fig. 2

From: Identification of MFGE8 and KLK5/7 as mediators of breast tumorigenesis and resistance to COX-2 inhibition

Fig. 2

COX-2-associated genes with high genetic alteration rate and expression in aggressive breast cancer. a Percentage of gene copy number amplification (orange) and mRNA upregulation (gray) of each of the 43 DEGs in TCGA-BRCA TNBC patient cohorts (n = 116). Genes to the left of the dashed lines were considered as highly amplified and expressed. b mRNA expression levels of final selected 10 candidate genes in various PAM50 breast cancer subtypes from the TCGA-BRCA dataset (n = 1247)

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