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Table 3 Prognostic values of baseline body mass index at diagnosis: Cox models

From: Impact of post-diagnosis weight change on survival outcomes in Black and White breast cancer patients

  Univariate analysis Multivariable analysis*
HR (95% CI) P HR (95% CI) P
Overall survival
 Categorical BMI
  Overweight vs. normal 1.65 (1.18–2.31) 0.004 1.23 (0.85–1.79) 0.27
  Obese vs. normal 1.85 (1.34–2.55) < 0.001 1.15 (0.79–1.65) 0.47
Continuous BMI, per 5 kg/m2 1.18 (1.10–1.28) < 0.001 1.09 (0.99–1.20) 0.073
Breast cancer-specific survival
 Categorical BMI
  Overweight vs. normal 1.86 (1.15–3.03) 0.012 1.72 (1.01–2.93) 0.045
  Obese vs. normal 1.74 (1.08–2.81) 0.023 1.36 (0.79–2.33) 0.27
Continuous BMI, per 5 kg/m2 1.11 (0.99–1.25) 0.079 1.01 (0.87–1.16) 0.92
Disease-free survival
 Categorical BMI
  Overweight vs. normal 1.65 (1.25–2.18) < 0.001 1.30 (0.96–1.76) 0.094
  Obese vs. normal 1.67 (1.28–2.19) < 0.001 1.09 (0.80–1.48) 0.59
Continuous BMI, per 5 kg/m2 1.15 (1.08–1.23) < 0.001 1.04 (0.96–1.13) 0.37
  1. *Adjusted for age, race, Carlson comorbidity index, tumor stage, histologic grade, estrogen receptor, progesterone receptor, Her2, radiotherapy, hormonal therapy, and chemotherapy in delayed entry Cox models
  2. Abbreviations: BMI body mass index, HR hazard ratio, CI confidence intervals