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Table 3 Prognostic values of baseline body mass index at diagnosis: Cox models

From: Impact of post-diagnosis weight change on survival outcomes in Black and White breast cancer patients

 

Univariate analysis

Multivariable analysis*

HR (95% CI)

P

HR (95% CI)

P

Overall survival

 Categorical BMI

  Overweight vs. normal

1.65 (1.18–2.31)

0.004

1.23 (0.85–1.79)

0.27

  Obese vs. normal

1.85 (1.34–2.55)

< 0.001

1.15 (0.79–1.65)

0.47

Continuous BMI, per 5 kg/m2

1.18 (1.10–1.28)

< 0.001

1.09 (0.99–1.20)

0.073

Breast cancer-specific survival

 Categorical BMI

  Overweight vs. normal

1.86 (1.15–3.03)

0.012

1.72 (1.01–2.93)

0.045

  Obese vs. normal

1.74 (1.08–2.81)

0.023

1.36 (0.79–2.33)

0.27

Continuous BMI, per 5 kg/m2

1.11 (0.99–1.25)

0.079

1.01 (0.87–1.16)

0.92

Disease-free survival

 Categorical BMI

  Overweight vs. normal

1.65 (1.25–2.18)

< 0.001

1.30 (0.96–1.76)

0.094

  Obese vs. normal

1.67 (1.28–2.19)

< 0.001

1.09 (0.80–1.48)

0.59

Continuous BMI, per 5 kg/m2

1.15 (1.08–1.23)

< 0.001

1.04 (0.96–1.13)

0.37

  1. *Adjusted for age, race, Carlson comorbidity index, tumor stage, histologic grade, estrogen receptor, progesterone receptor, Her2, radiotherapy, hormonal therapy, and chemotherapy in delayed entry Cox models
  2. Abbreviations: BMI body mass index, HR hazard ratio, CI confidence intervals