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Fig. 1 | Breast Cancer Research

Fig. 1

From: Immunohistochemical analysis of adipokine and adipokine receptor expression in the breast tumor microenvironment: associations of lower leptin receptor expression with estrogen receptor-negative status and triple-negative subtype

Fig. 1

These images represent relatively average immunohistochemical expression of the adipokines and adipokine receptors in invasive breast tumor tissues. The specimens shown in a through e are imaged at × 20 magnification and show LEP (a), LEPR (b), ADIPOQ (c), ADIPOR1 (d), and ADIPOR2 (e) immunoreactivity in invasive breast tumor tissues. The images in f through j are further magnified images of each core shown in a through e. TMA cores were mostly 0.6 μm (with a range of 0.6 to 1.2 μm). Presence of granular cytoplasmic pattern of staining of the adipokines and adipokine receptors in the breast tumor tissues ranged in intensity from weakly positive (shown in images d and e—and the corresponding magnified images i and j) to moderate and strong (shown in images a–c—and the corresponding magnified images f–h)

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