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Fig. 3 | Breast Cancer Research

Fig. 3

From: ESR1 mutations are frequent in newly diagnosed metastatic and loco-regional recurrence of endocrine-treated breast cancer and carry worse prognosis

Fig. 3

Survival analysis for patients with loco-regional recurrence. a Kaplan-Meier plots of distant recurrence-free survival from the primary tumor comparing ESR1 mutations at an allele frequency higher versus lower than 1%. b Kaplan-Meier plots of disease-free survival from the tested local recurrence comparing ESR1 mutations at an allele frequency higher versus lower than 1%. c Kaplan-Meier plots of distant recurrence-free survival from the tested local recurrence comparing ESR1 mutations at an allele frequency higher versus lower than 1%. d–f Univariate Cox regression analysis for the same comparisons as in a–c represented by forest plots showing the hazard ratio for the various clinical parameters. LNDx, lymph node status at diagnosis; LR type, local or regional; error lines represent the 95% confidence interval

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