Fig. 3
From: Cathepsin V suppresses GATA3 protein expression in luminal A breast cancer
CTSV expression is inversely correlated with GATA3 expression. a, b Western blotting analysis of GATA3 protein expression in MCF-7 and ZR-75-1 shCTSV line models. c, d Western blotting analysis of GATA3 expression in MCF-7 and ZR-75-1 cells after overexpression of wildtype CTSV (wtCTSV) or a catalytic cysteine mutant CTSV (mtCTSV). GAPDH was used as an internal loading control for all Western blotting analysis. g Linear regression analysis and Spearman’s correlation between GATA3 protein expression (RPPA) and CTSV mRNA expression (microarray) in ER-positive breast patients from the TCGA 2012 breast invasive carcinoma dataset (cBioPortal)