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Table 1 EGFR-targeted and non-targeted antibody-drug conjugates

From: Navitoclax enhances the effectiveness of EGFR-targeted antibody-drug conjugates in PDX models of EGFR-expressing triple-negative breast cancer

ADC Antibody Linker Payload
ABT-414 ABT-806 mc (non-cleavable) MMAF
AB095-MMAF AB095 mc (non-cleavable) MMAF
ABBV-321 ABT-806 AM1 mc-VC (cleavable) PBD
AB095-PBD AB095 mc-VC (cleavable) PBD