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Table 2 The median number ± standard deviation of lymphocytes per μl is indicated for 14 stage IV metastatic IBC patients and 11 healthy donors as assessed using BD Trucount™ assays

From: Immune phenotype of patients with stage IV metastatic inflammatory breast cancer

  IBC patients Healthy donors p values
Total lymphocytes per μl 897 ± 413 1976 ± 855 0.00018
CD3+ T cells per μl 646 ± 350 1496 ± 762 0.00051
CD8+ T cells per μl 222 ± 117 458 ± 215 0.015
CD4+ T cells per μl 372 ± 236 873 ± 701 0.00093
CD4+CD8+ cells per μl 6 ± 5 14 ± 104 0.0030
NK cells per μl 117 ± 80 296 ± 142 0.00076
B cells per μl 137 ± 101 223 ± 96 0.017
CD4/CD8 ratio 1.7 ± 0.7 2.6 ± 1.6 0.023
CD4+ central memory cells per μl 165 ± 88 335 ± 296 0.00051
CD4+ effector cells per μl 1 ± 29 12 ± 13 0.0034
CD4+ effector memory cells per μl 68 ± 39 136 ± 91 0.0016
CD4+ naïve cells per μl 125 ± 126 382 ± 330 0.00093
CD8+ central memory cells per μl 20 ± 32 49 ± 32 0.0048
CD8+ effector cells per μl 43 ± 39 87 ± 56 0.37
CD8+ effector memory cells per μl 46 ± 54 112 ± 77 0.035
CD8+ naïve cells per μl 89 ± 68 168 ± 131 0.052
CD16 GMFI on CD56bright NK cells 4896 ± 3883 3224 ± 1361 0.023
Granzyme B GMFI on CD56bright NK cells 1257 ± 1064 578 ± 474 0.049
Perforin GMFI on CD56bright NK cells 9412 ± 18,059 4564 ± 4717 0.049
  1. All comparisons with significant p values < 0.05 also passed false discovery rate testing