Fig. 5

Associations between chromosome-specific telomere length and cognitive measures. Scatter plots of visual memory scores (Y-axis) against telomere lengths for chromosome 17 (X-axis) are shown, stratified by time-point. The chromosome 17 telomere values for the short arm (open blue circle) and long arm (solid orange circle) of each individual are connected by broken lines, with the telomere values being shown on the X-axis and the visual memory scores being shown on the Y-axis. Comparing the plots from the baseline data (time-point 1) (a) to those of the mid-chemo data (time-point 2) (b), one can see the generalized pattern of telomere shortening (shift of values to left) with decreases in visual memory scores (downward shift of values with tighter clustering)