Mean changes in chromosome-specific telomere values at baseline (T1) compared to mid-chemotherapy cycle (T2) Time-points. A negative value (shortening) was observed at the mid-chemo time-point for 38 of the 46 chromosomal arms. The X-axis shows values for each chromosomal arm. The Y-axis shows mean differences in telomere values. The bars on the histograms indicate standard errors. Abbreviations: p = short arm; q = long arm.