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Fig. 4 | Breast Cancer Research

Fig. 4

From: Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer—insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system

Fig. 4

Gene expression (RT-qPCR) for the ED03 and EDW01 PDX models. Mean of individual xenograft tumours are shown, where n ≥ 3 error bars are shown (standard error of the mean). For ED03: p3 n = 1, p5 n = 1, p7 n = 2, p8 n = 1, p9 n = 3, p10 n = 3, p = 11 n = 3. For EDW01: VIM/CDH1 and for ITGAB1/A2/ILK: p3 n = 6, p4 n = 11, p5 n = 6, p6 n = 11, p7 n = 3; for CD24/CD44 and murine Itgb1, all passages were n = 3. dCT in the figure represents delta CT, or change in CT values calculated by subtracting the raw CT of the gene of interest from the raw CT of the housekeeping gene RPL32. Statistical significance was calculated using two-tailed Mann-Whitney test (Non-parametric). *p < 0.05, **p < 0.01, ***p < 0.001

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Breast Cancer Research

ISSN: 1465-542X

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