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Table 2 EVs alter expression of genes related to cancer progression in treated breast cancer cells

From: Extracellular vesicles from young women’s breast cancer patients drive increased invasion of non-malignant cells via the Focal Adhesion Kinase pathway: a proteomic approach

  1. NanoString analysis of differential gene expression in cells after treatment with EVs from YWBC patients, healthy donors (HD), MDA-231 cells, or untreated controls identified via nSolver software. Genes associated with invasion (EMT, metastasis, or cell motility) are shown in yellow, cell adhesion in green, angiogenesis in blue, and proliferation and tumor growth in orange. Negative log2FC values indicate decreases in gene expression in cells treated with EVs from YWBC patients relative to those treated with HD (left) or in cells treated with EVs from MDA-MB231 cells relative to untreated cells (right)