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Table 2 Effect of body mass index (BMI) on the rate of pathological complete response (pCR)

From: Effect of body mass index on response to neo-adjuvant therapy in HER2-positive breast cancer: an exploratory analysis of the NeoALTTO trial

BMI with 4 categories

pCR (%)

N

Univariate

OR (95%CI)

Univariate

p value

Multivariate^

OR (95%CI)

Multivariate

p value

BMI at baseline

160 (35.2)

454

    

 Normal weight

77 (35.0)

220

 Underweight

8 (57.1)

14

2.48 (0.83–7.39)

0.104

3.30 (1.07–10.12)

0.037

 Overweight

42 (30.7)

137

0.82 (0.52–1.30)

0.398

0.78 (0.49–1.25)

0.309

 Obese

33 (39.8)

83

1.23 (0.73–2.06)

0.443

1.28 (0.75–2.18)

0.362

  1. BMI body mass index, pCR pathological complete response, OR odds ratio, CI confidence interval
  2. ^Adjusted for planned surgery, HR, nodal status, and tumor size