Table 1 Patient characteristics in each treatment arm
Characteristic | FEC → Doc | FEC → Doc/Gem | ||
|---|---|---|---|---|
Mean or n | SD or % | Mean or n | SD or % | |
Age | 53.9 | 10.4 | 53.1 | 10.6 |
BMI | 26.3 | 5.1 | 26.2 | 5. |
Tumor stage | ||||
pT1 | 771 | 40.6 | 781 | 42.1 |
pT2 | 992 | 52.3 | 960 | 51.7 |
pT3 | 109 | 5.7 | 89 | 4.8 |
pT4 | 26 | 1.4 | 26 | 1.4 |
Grade | ||||
G1 | 79 | 4.2 | 97 | 5.2 |
G2 | 914 | 48.2 | 891 | 48.0 |
G3 | 905 | 47.7 | 868 | 46.8 |
Nodal status | ||||
pN+ | 1264 | 66.6 | 1217 | 65.6 |
pN0 | 634 | 33.4 | 639 | 34.4 |
Tumor type | ||||
Ductal | 1558 | 82.1 | 1524 | 82.1 |
Lobular | 213 | 11.2 | 206 | 11.1 |
Other | 127 | 6.7 | 126 | 6.8 |
ER | ||||
Negative | 610 | 32.1 | 642 | 34.6 |
Positive | 1288 | 67.9 | 1214 | 65.4 |
PR | ||||
Negative | 768 | 40.5 | 757 | 40.8 |
Positive | 1130 | 59.5 | 1099 | 59.2 |
HER2 | ||||
Negative | 1457 | 76.8 | 1413 | 76.1 |
Positive | 441 | 23.2 | 443 | 23.9 |
Menopausal status | ||||
Premenopausal | 775 | 40.8 | 790 | 42.6 |
Postmenopausal | 1123 | 59.2 | 1066 | 57.4 |
Adjuvant antihormonal therapy | 1360 | 72.3 | 1317 | 71.4 |
Adjuvant trastuzumab therapy | 378 | 20.1 | 376 | 20.4 |
Adjuvant radiotherapy | 1601 | 85.1 | 1553 | 84.2 |