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Table 2 Multivariable Cox proportional hazard model showing gene alterations associated with time to relapses

From: Inter-tumor genomic heterogeneity of breast cancers: comprehensive genomic profile of primary early breast cancers and relapses

Variables

Contrast

HR

Low 95

Up 95

p value

TP53 mutations

Yes vs no

1.85

1.07

3.21

0.02

MYC copy number gain

Yes vs no

1.71

1.01

2.92

0.04

pT

2–4 vs 1

2.41

1.49

3.89

< 0.001

Molecular subtypes

TN vs others

2.34

1.36

4.04

0.002

  1. HR hazard ratio, TN triple negative