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Fig. 3 | Breast Cancer Research

Fig. 3

From: Inter-tumor genomic heterogeneity of breast cancers: comprehensive genomic profile of primary early breast cancers and relapses

Fig. 3

Distribution of driver and VUS alterations in 61 matched primary tumors and relapses. Each column represents one case, with primary tumors in blank columns and matched relapses in dashed columns. The cases were grouped according to the molecular subtype (luminal B, triple negative or HER2-non luminal) and the recurrence site (distant vs loco-regional) color-coded as in the legend. The most frequently altered genes (occurring in more than 5% of samples) and the type of alterations (driver or VUS) were reported in rows and color-coded according to the legend. The total number of alterations affecting each sample was shown in the lower part of the figure

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