Fig. 8

Quantification of the western blot data for patients that benefited from trastuzumab-based therapies shown in Fig. 7a. The data for patient 1 (a), patient 2 (b), patient 4 (c), patient 5 (d), patient 7 (e), patient 8 (f), and patient 9 (g) are shown. Note that statistical analysis of the data was not possible as blood was collected from each patient only once at each time point. In the case of patient 9, an apparent increase in the GNAS2 level on day 21 likely reflects artifacts (“image artifacts?”) on the respective image (see Fig. 7)