Statin use | Metformin use | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Total | Ever users | Never users | Ever users | Never users | ||||||||
n | % | n | % | n | % | n | % | n | % | |||
Total (row percent) | 770 | 100.0 | 209 | 27.1 | 561 | 72.9 | 102 | 13.2 | 668 | 86.8 | ||
Medication use | ||||||||||||
Metformin ever | 102 | 13.25 | 69 | 33.01 | 33 | 5.88 | ** | 102 | 100.0 | 0 | 0.00 | |
Statin ever | 209 | 27.14 | 209 | 100.0 | 0 | 0.00 | 69 | 67.65 | 140 | 20.96 | ** | |
Insulin ever | 31 | 4.03 | 20 | 9.57 | 11 | 1.96 | ** | 16 | 15.69 | 15 | 2.25 | ** |
Hormone replacement therapy ever | 32 | 4.16 | 10 | 4.78 | 22 | 3.92 | 5 | 4.90 | 27 | 4.04 | ||
Aspirin ever | 159 | 20.65 | 82 | 39.23 | 77 | 13.73 | ** | 45 | 44.12 | 114 | 17.07 | ** |
Anti-hypertension medications ever | 294 | 38.18 | 133 | 63.64 | 161 | 28.70 | ** | 69 | 67.65 | 225 | 33.68 | ** |
Demographic and medical factors | ||||||||||||
Age | ||||||||||||
40 to < 45 | 107 | 13.90 | 8 | 3.83 | 99 | 17.65 | ** | 3 | 2.94 | 104 | 15.57 | ** |
45 to < 50 | 170 | 22.08 | 22 | 10.53 | 148 | 26.38 | 11 | 10.78 | 159 | 23.80 | ||
50 to < 55 | 218 | 28.31 | 48 | 22.97 | 170 | 30.30 | 33 | 32.35 | 185 | 27.69 | ||
55–61 | 275 | 35.71 | 131 | 62.68 | 144 | 25.67 | 55 | 53.92 | 220 | 32.93 | ||
Mean [SD] | 51.96 [5.63] | 55.11 [4.64] | 50.78 [5.52] | ** | 54.64 [4.38] | 51.55 [5.69] | ** | |||||
Education | ||||||||||||
High school or less | 359 | 46.62 | 114 | 54.55 | 245 | 43.67 | * | 63 | 61.76 | 296 | 44.31 | ** |
Some college | 179 | 23.25 | 48 | 22.97 | 131 | 23.35 | 20 | 19.61 | 159 | 23.80 | ||
At least Bachelor’s | 232 | 30.13 | 47 | 22.49 | 185 | 3298 | 19 | 18.63 | 213 | 31.89 | ||
Race/ethnicity | ||||||||||||
Hispanic | 604 | 78.44 | 176 | 84.21 | 428 | 76.29 | * | 81 | 79.41 | 523 | 78.29 | |
Non-Hispanic white | 60 | 7.79 | 8 | 3.83 | 52 | 9.27 | 2 | 1.96 | 58 | 8.68 | ||
Non-Hispanic black | 88 | 11.43 | 20 | 9.57 | 68 | 12.12 | 16 | 15.69 | 72 | 10.78 | ||
Non-Hispanic, Asian, or other race | 18 | 2.34 | 5 | 2.39 | 13 | 2.32 | 3 | 2.94 | 15 | 2.25 | ||
Diabetes | ||||||||||||
Any | 160 | 20.78 | 86 | 41.15 | 74 | 13.19 | ** | 94 | 92.16 | 66 | 9.88 | ** |
Type 1 | 12 | 1.56 | 8 | 3.83 | 4 | 0.71 | ** | 9 | 8.82 | 3 | 0.45 | ** |
Type 2 | 100 | 12.99 | 68 | 32.54 | 32 | 5.70 | ** | 82 | 80.39 | 18 | 2.69 | ** |
Gestational | 72 | 9.35 | 27 | 12.92 | 45 | 8.02 | * | 23 | 22.55 | 49 | 7.34 | ** |
BMI | ||||||||||||
18.5 to < 25 | 134 | 17.40 | 26 | 12.44 | 108 | 19.25 | * | 11 | 10.78 | 123 | 18.41 | ** |
25 to < 30 | 247 | 32.08 | 62 | 29.67 | 185 | 32.98 | 19 | 18.63 | 228 | 34.13 | ||
30 to < 35 | 215 | 27.92 | 65 | 31.10 | 150 | 26.74 | 37 | 36.27 | 178 | 26.65 | ||
≥ 35 | 174 | 22.60 | 56 | 26.79 | 118 | 21.03 | 35 | 34.31 | 139 | 20.81 | ||
Mean [SD] | 30.91 [6.56] | 31.80 [6.27] | 30.58 [6.64] | * | 33.67 [6.66] | 30.49 [5.69] | ** | |||||
Reproductive history | ||||||||||||
Age at menarche | ||||||||||||
< 12 | 204 | 26.49 | 45 | 21.53 | 159 | 28.34 | 26 | 25.49 | 178 | 26.65 | ||
12 | 138 | 17.92 | 37 | 17.70 | 101 | 18.00 | 20 | 19.61 | 118 | 17.66 | ||
13 | 167 | 21.69 | 52 | 24.88 | 115 | 20.50 | 26 | 25.49 | 141 | 21.11 | ||
> 14 | 258 | 33.51 | 73 | 34.93 | 185 | 32.98 | 29 | 28.43 | 229 | 34.28 | ||
Missing | 3 | 0.39 | 2 | 0.96 | 1 | 0.18 | 1 | 0.98 | 2 | 0.30 | ||
Parity | ||||||||||||
Nulliparous | 101 | 13.12 | 27 | 12.92 | 74 | 13.19 | 11 | 10.78 | 90 | 13.47 | ||
1–2 children | 368 | 47.79 | 99 | 47.37 | 269 | 47.95 | 48 | 47.06 | 320 | 47.90 | ||
3 or more children | 301 | 39.09 | 83 | 39.71 | 218 | 38.86 | 43 | 42.16 | 258 | 38.62 | ||
Age at first live birth | ||||||||||||
Nulliparous | 101 | 13.12 | 27 | 12.92 | 74 | 13.19 | 11 | 10.78 | 90 | 13.47 | ||
< 25 years old | 400 | 51.95 | 114 | 54.55 | 286 | 50.98 | 63 | 61.76 | 337 | 50.45 | ||
25 to < 35 years old | 212 | 27.53 | 55 | 26.32 | 157 | 27.99 | 23 | 22.55 | 189 | 28.29 | ||
> 35 years old | 57 | 7.40 | 13 | 6.22 | 44 | 7.84 | 5 | 4.90 | 52 | 7.78 | ||
Breast cancer risk factors | ||||||||||||
Post-menopause | 455 | 59.09 | 179 | 85.65 | 276 | 49.20 | ** | 78 | 76.47 | 377 | 56.44 | ** |
First-degree family history of breast cancer | 95 | 12.34 | 23 | 11.00 | 72 | 12.83 | 15 | 14.71 | 80 | 11.98 | ||
Age at menopause, mean [SD] | 46.39 [6.30] | 45.77 [6.60] | 46.78 [6.09] | 45.63 [6.91] | 46.54 [6.18] |