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Table 3 Multivariable-adjusted hazard ratios (95% CI) for associations of aspirin use and risk of triple-negative breast cancer in the BWHS, 1995–2017

From: Aspirin use and risk of breast cancer in African American women

Aspirin use

 

Triple negative (n = 284)

Person-years

Cases

HRa

95% CI

HRb

95% CI

Non-use

674,961

178

1.00

Reference

1.00

Reference

Past use

143,603

61

0.98

0.72, 1.32

0.99

0.72, 1.35

Current use

149,804

45

0.66

0.47, 0.94

0.70

0.49, 0.99

Duration of current use

 Current, < 5 years

36,817

14

0.48

0.28, 0.84

0.50

0.29, 0.87

 Current, 5–10 years

20,923

18

0.92

0.56, 1.51

0.98

0.59, 1.61

 Current, ≥ 10 years

17,183

13

0.70

0.39, 1.27

0.75

0.41, 1.37

  1. aAdjusted for age
  2. bAdjusted for age, first-degree family history of breast cancer, menopausal status, recent BMI duration of E+P use, parity, age at first birth, age at menarche, recency of OC use, alcohol consumption, physical activity, and lactation