Table 1 Characteristics of the study population (n = 1040) at blood draw and study entry
From: Hormonal determinants of mammographic density and density change
Characteristic | No. | Mean (SD) or % |
Age at blood draw, years | 1040 | 57.9 (9.3) |
BMI at study entry, kg/m2 | 1040 | 25.3 (4.0) |
Age at menarche, years | 1016 | 13.2 (1.5) |
Ever use of contraceptives, % | 1028 | 83.9 |
Number of births, n | 1039 | 1.9 (1.1) |
Age at first birth, years | 921 | 26.8 (5.2) |
Postmenopausal, n | 705 | 67.8 |
Age at menopause, years | 371 | 49.6 (5.4) |
Alcohol consumption, g/day | 1035 | 6.9 (8.3) |
Physical activity, MET-h/d | 1040 | 42.4 (6.4) |
Previous use of MHT, % | 1040 | 24.4 |
Mammographic features | ||
Mammographic density, dense area, cm2 | 1040 | 24.9 (22.2) |
Mammographic density change, dense area, cm2/year | 1040 | − 0.8 (3.3) |
Circulating hormones | Median (SD) | |
Progestogens | ||
Pregnenolone, ng/mL | 718 | 5.3 (10.2) |
Progesterone, ng/mL | 905 | 3.9 (22.4) |
17OH-progesterone, ng/mL | 910 | 2.1 (11.4) |
Androgens | ||
DHEA, ng/mL | 768 | 22.0 (45.2) |
DHEAS, μg/mL | 974 | 1.8 (2.2) |
Androstenedione, ng/mL | 817 | 4.8 (24.6) |
Testosterone, ng/mL | 829 | 2.0 (11.1) |
Free testosterone, pg/mL | 824 | 46.6 (312.0) |
Androsterone, ng/mL | 711 | 13.1 (17.0) |
Etiocholanolone, ng/mL | 654 | 6.1 (10.4) |
Oestrogens | ||
Oestrone, ng/mL | 450 | 6.3 (21.5) |
Oestrone sulphate, ng/mL | 938 | 7.1 (21.3) |
Corticoids | ||
Corticosterone, ng/mL | 915 | 4.1 (14.4) |
Aldosterone, ng/mL | 565 | 0.8 (2.5) |
11-Deoxycortisol, ng/mL | 866 | 3.2 (15.1) |
Cortisol, ng/mL | 914 | 128.8 (61.7) |
Cortisone, ng/mL | 909 | 44.7 (35.1) |
Peptide hormones and proteins | ||
Prolactin, ng/mL | 1035 | 15.4 (14.2) |
SHBG, μg/mL | 1034 | 4.1 (2.4) |