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Fig. 2 | Breast Cancer Research

Fig. 2

From: Clinical implications of prospective genomic profiling of metastatic breast cancer patients

Fig. 2

Metastatic mutational landscape. a Oncoplot of somatic mutations identified at a frequency of 10% or more in sequenced metastatic samples (n = 168). Percentage frequency of the genes is shown in the barchart to the left of the central plot. Clinical subtype and mutation type are indicated on their respective legend. For genes significantly enriched in this cohort compared to TCGA, see Supplementary Table 1. b Mutational co-occurrence plot for metastatic ER+HER2− samples (n = 112). Degree of significance indicated in the legend, with only results of the top 25 genes shown. No mutational exclusivity pairs were identified. For individual p values, see Supplementary Table 2

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