Table 2 Treatment exposure, described by randomized arm, as well as within the subgroup aged ≥ 75. Reported as n (%) unless otherwise stated
Regimen received | Arm A, 100 mg/m2 | Arm B, 125 mg/m2 | ||
|---|---|---|---|---|
All (N = 79) | Pts aged 75+ (N = 33) | All (N = 79) | Pts aged 75+ (N = 33) | |
Total n of cycles | 594 | 214 | 443 | 180 |
Median n cycles (range) | 6 (1–28) | 6 (1–19) | 6 (1–22) | 5 (1–11) |
Dose delays | ||||
N of patients | 52 (66) | 19 (58) | 50 (63) | 18 (55) |
N of cycles | 127 (21) | 43 (20) | 100 (23) | 35 (19) |
Dose reductions | ||||
N of patients | 57 (72) | 22 (68) | 63 (80) | 23 (70) |
N of cycles | 234 (39) | 78 (36) | 257 (58) | 101 (56) |