Table 2 Breast cancer odds ratio (ORs) in relation to participant’s perinatal exposures
From: Perinatal and postnatal exposures and risk of young-onset breast cancer
Characteristics | Controls (n = 1672) | Cases (n = 1473) | OR (95% CI) | OR (95% CI) |
|---|---|---|---|---|
Preeclampsia/eclampsia/toxemia | ||||
No | 1163 (98.4) | 1026 (97.9) | 1.00 | 1.00 |
Yes | 19 (1.6) | 22 (2.1) | 1.92 (0.82–4.51)¥ | 2.28 (0.89–5.82)€ |
Gestational hypertension§ | ||||
No | 1121 (97.6) | 968 (97.9) | 1.00 | 1.00 |
Yes | 28 (2.4) | 21 (2.1) | 0.84 (0.44–1.59)¥ | 1.00 (0.50–2.00)€ |
Any hypertensive disorder | ||||
No | 1158 (96.1) | 1029 (96.0) | 1.00 | 1.00 |
Yes | 47 (3.9) | 43 (4.0) | 1.12 (0.66–1.91)¥ | 1.40 (0.78–2.52)€ |
Maternal smoking | ||||
No | 935 (70.6) | 821 (70.0) | 1.00 | |
Yes | 389 (29.4) | 352 (30.0) | 1.19 (0.81–1.74)* | |
Low birth weight | ||||
Birth weight > 5.5 pounds | 1226 (93.2) | 1082 (92.2) | 1.00 | 1.00 |
Birth weight ≤ 5.5 pounds | 90 (6.8) | 91 (7.8) | 1.14 (0.80–1.62) | 1.05 (0.70–1.59)Ŧ |
High birth weight | ||||
Birth weight < 8.8 pounds | 881 (92.3) | 771 (90.2) | 1.00 | 1.00 |
Birth weight ≥ 8.8 pounds | 74 (7.87 | 84 (9.8) | 1.59 (1.07–2.36) | 1.44 (0.93–2.22)Ŧ |
Breastfed | ||||
No | 780 (59.6) | 726 (62.4) | 1.00 | |
Yes | 528 (40.4) | 437 (37.6) | 0.76 (0.58–1.00) | |
Soy-fed (formula made from soy) | ||||
No | 1021 (95.9) | 898 (95.4) | 1.00 | |
Yes | 44 (4.1) | 43 (4.6) | 1.04 (0.66–1.65) | |
DES exposure during pregnancy | ||||
No | 1042 (97.0) | 933 (97.4) | 1.00 | |
Yes | 32 (3.0) | 25 (2.6) | 0.82 (0.44–1.54) | |
Short gestational length at birth | ||||
Born ≥ 38 weeks | 561 (88.1) | 490 (85.1) | 1.00 | 1.00 |
Born < 38 weeks | 76 (11.9) | 86 (14.9) | 1.36 (0.91–2.02) | 1.26 (0.83–1.92)Ŧ |