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Table 3 Results of the digitalMLPA BRCA2 classifier in the training and test sets

From: BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer

 

Predicted with digitalMLPA

Class error rate (%)

BRCA2-like

Non-BRCA2-like

Array-based score

Training set

  BRCA2-like

21

4

16

  Non-BRCA2-like

2

28

7

  Overall error rate

  

11

Test set

  BRCA2-like

21

7

25

  Non-BRCA2-like

3

25

11

  Overall error rate

  

18

Performance in test set

  Sensitivity = 75%

   

  Specificity = 89%

   

  Accuracy = 82%

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