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Table 2 Description of individual patients in OM cohort

From: Patient treatment and outcome after breast cancer orbital and periorbital metastases: a comprehensive case series including analysis of lobular versus ductal tumor histology

PatientHistology of primary breast cancerSite of first distant metastasisTime to first distant metastasis in monthsLocation of OMTime to OM in monthsSide of OMLocation of XRT therapy to OMSurvival in months after OMCNS metastasisNumber of systemic therapy lines for metastatic cancer
1IDCOphthalmic86.8Orbital bone, Rectus muscles86.8RightOrbital bone55.8 (alive)No2
2IDCAdrenal glands, bone, CNS, distant lymph nodes, liver178.1Choroid, ciliary body294.1RightChoroid79.0Yes8
3IDCOphthalmic, bone8.2Retro-orbital fat, globe, orbital bone8.2RightOrbital bone20.1No5
4IDCDistant lymph node14.3Rectus muscles, lacrimal gland, orbital bone58.2RightOrbital bone35.5No11
5IDCBone, spleen96.0Retro-orbital fat153.8BilateralNo XRT0.2Yes6
6IDCOphthalmic, bone, liver0Orbital bone0LeftNo XRT14.3Yes3
7IDCOphthalmic, CNS26.8Choroid, retina26.8RightChoroid55.2Yes3
8IDCOphthalmic, bone14.1Orbital bone14.1LeftOrbital bone1.7No0
9IDCLung10.9Retina23.8LeftRetina1.8Yes3
10IDCBone, liver20.7Orbital bone, Periorbital soft tissue69.8LeftOrbital bone22.8 (alive)No5
11IDCBone59.1Orbital soft tissue101.6LeftNo XRT1.0Yes4
12IDCDistant lymph nodes, lung59.8Globe83.5LeftNo XRT1.1Yes8
13IDCContralateral breast, distant lymph nodes0Eyelid, periorbit51.1LeftEyelidLost to follow-upYes4
14IDCOphthalmic26.0Rectus muscle26.0RightNo XRT91.3Yes6
15ILCBone, distant lymph nodes0Orbital bone, eye lid, lacrimal gland41.6BilateralOrbital bone, eyelid12.1No8
16ILCOphthalmic35.0Rectus muscles35.0LeftNo XRT3.0No1
17ILCOphthalmic, bone70Rectus muscle70.0RightOrbital bone4.6Yes2
18ILCOphthalmic, peritoneum0Retina, choroid, rectus muscle0LeftNo XRT14.1No0
19ILCOphthalmic, bone0Rectus muscles0BilateralNo XRT41.3No5
20ILCOphthalmic33.4Eyelid, periorbital soft tissue, orbital bone33.4BilateralBoth eyelids21.5No2
21ILCBone74.0Rectus muscle, orbital bone102.8BilateralOrbital boneLost to follow-upNo5
22ILCBone, contralateral breast, thyroid gland119.2Orbital bone, eyelid153.1RightOrbital bone8.7Yes7
23ILCCNS36.6Retrobulbar soft tissue42.2LeftTwice retrobulbar1.8Yes3
24Mixed IDC and ILCRectum82.6Rectus muscles, eyelid94.0BilateralRetrobulbar, eyelid24.7No5
25Mixed IDC and ILCBone34.9Orbital bone41.6BilateralOrbital bone8.7Yes3
26UnknownOphthalmic, bone165.0Orbital bone, rectus muscles165RightOrbital bone14.2No0
27UnknownGastrointestinal tract, peritoneum0Rectus muscles, eyelid, orbital bone2.8BilateralRetrobulbar4.3No2
28UnknownBone122.7Orbital and periorbital soft tissue140.5BilateralRetrobulbar10.0Yes3
  1. XRT radiation therapy