Table 2 Description of individual patients in OM cohort
Patient | Histology of primary breast cancer | Site of first distant metastasis | Time to first distant metastasis in months | Location of OM | Time to OM in months | Side of OM | Location of XRT therapy to OM | Survival in months after OM | CNS metastasis | Number of systemic therapy lines for metastatic cancer |
|---|---|---|---|---|---|---|---|---|---|---|
1 | IDC | Ophthalmic | 86.8 | Orbital bone, Rectus muscles | 86.8 | Right | Orbital bone | 55.8 (alive) | No | 2 |
2 | IDC | Adrenal glands, bone, CNS, distant lymph nodes, liver | 178.1 | Choroid, ciliary body | 294.1 | Right | Choroid | 79.0 | Yes | 8 |
3 | IDC | Ophthalmic, bone | 8.2 | Retro-orbital fat, globe, orbital bone | 8.2 | Right | Orbital bone | 20.1 | No | 5 |
4 | IDC | Distant lymph node | 14.3 | Rectus muscles, lacrimal gland, orbital bone | 58.2 | Right | Orbital bone | 35.5 | No | 11 |
5 | IDC | Bone, spleen | 96.0 | Retro-orbital fat | 153.8 | Bilateral | No XRT | 0.2 | Yes | 6 |
6 | IDC | Ophthalmic, bone, liver | 0 | Orbital bone | 0 | Left | No XRT | 14.3 | Yes | 3 |
7 | IDC | Ophthalmic, CNS | 26.8 | Choroid, retina | 26.8 | Right | Choroid | 55.2 | Yes | 3 |
8 | IDC | Ophthalmic, bone | 14.1 | Orbital bone | 14.1 | Left | Orbital bone | 1.7 | No | 0 |
9 | IDC | Lung | 10.9 | Retina | 23.8 | Left | Retina | 1.8 | Yes | 3 |
10 | IDC | Bone, liver | 20.7 | Orbital bone, Periorbital soft tissue | 69.8 | Left | Orbital bone | 22.8 (alive) | No | 5 |
11 | IDC | Bone | 59.1 | Orbital soft tissue | 101.6 | Left | No XRT | 1.0 | Yes | 4 |
12 | IDC | Distant lymph nodes, lung | 59.8 | Globe | 83.5 | Left | No XRT | 1.1 | Yes | 8 |
13 | IDC | Contralateral breast, distant lymph nodes | 0 | Eyelid, periorbit | 51.1 | Left | Eyelid | Lost to follow-up | Yes | 4 |
14 | IDC | Ophthalmic | 26.0 | Rectus muscle | 26.0 | Right | No XRT | 91.3 | Yes | 6 |
15 | ILC | Bone, distant lymph nodes | 0 | Orbital bone, eye lid, lacrimal gland | 41.6 | Bilateral | Orbital bone, eyelid | 12.1 | No | 8 |
16 | ILC | Ophthalmic | 35.0 | Rectus muscles | 35.0 | Left | No XRT | 3.0 | No | 1 |
17 | ILC | Ophthalmic, bone | 70 | Rectus muscle | 70.0 | Right | Orbital bone | 4.6 | Yes | 2 |
18 | ILC | Ophthalmic, peritoneum | 0 | Retina, choroid, rectus muscle | 0 | Left | No XRT | 14.1 | No | 0 |
19 | ILC | Ophthalmic, bone | 0 | Rectus muscles | 0 | Bilateral | No XRT | 41.3 | No | 5 |
20 | ILC | Ophthalmic | 33.4 | Eyelid, periorbital soft tissue, orbital bone | 33.4 | Bilateral | Both eyelids | 21.5 | No | 2 |
21 | ILC | Bone | 74.0 | Rectus muscle, orbital bone | 102.8 | Bilateral | Orbital bone | Lost to follow-up | No | 5 |
22 | ILC | Bone, contralateral breast, thyroid gland | 119.2 | Orbital bone, eyelid | 153.1 | Right | Orbital bone | 8.7 | Yes | 7 |
23 | ILC | CNS | 36.6 | Retrobulbar soft tissue | 42.2 | Left | Twice retrobulbar | 1.8 | Yes | 3 |
24 | Mixed IDC and ILC | Rectum | 82.6 | Rectus muscles, eyelid | 94.0 | Bilateral | Retrobulbar, eyelid | 24.7 | No | 5 |
25 | Mixed IDC and ILC | Bone | 34.9 | Orbital bone | 41.6 | Bilateral | Orbital bone | 8.7 | Yes | 3 |
26 | Unknown | Ophthalmic, bone | 165.0 | Orbital bone, rectus muscles | 165 | Right | Orbital bone | 14.2 | No | 0 |
27 | Unknown | Gastrointestinal tract, peritoneum | 0 | Rectus muscles, eyelid, orbital bone | 2.8 | Bilateral | Retrobulbar | 4.3 | No | 2 |
28 | Unknown | Bone | 122.7 | Orbital and periorbital soft tissue | 140.5 | Bilateral | Retrobulbar | 10.0 | Yes | 3 |