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Table 1 Distribution of patient characteristics and CAP1 expression

From: Effects of tumor-specific CAP1 expression and body constitution on clinical outcomes in patients with early breast cancer

   Patients with tumor in TMA
(n = 718)
 
Patient characteristics
n (%) or median (IQR)
All patients
(n = 910)
Low CAP1
(n = 106)
Moderate CAP1
(n = 273)
High CAP1
(n = 290)
Ptrend Non-assessable
(n = 49)
Not included in TMA
(n = 192)
Age at baseline
 Continuous [years] 55.4 (50.0–61.7) 56.2 (51.9–62.2) 56.2 (50.6–61.7) 53.5 (49.0–59.4) < 0.001a 52.3 (48.2–57.4) 58.2 (51.7–62.3)
Menopause
 Premenopausal 68 (7.9) 4 (3.9) 21 (8.0) 23 (8.3) 0.216b 5 (11.1) 15 (8.5)
 Postmenopausal 792 (92.1) 98 (96.1) 240 (92.0) 253 (91.7) 40 (88.9) 161 (91.5)
 Missing 50 4 12 14   4 16
Height
 Continuous [cm] 165.0 (160.0–168.0) 164.5 (161.0–167.3) 164.0 (160.0–168.0) 165.0 (161.0–169.0) 0.091a 163.0 (160.0–167.5) 165.0 (161.0–168.0)
Weight
 Continuous [kg] 68.0 (61.0–75.0) 69.0 (60.8–77.3) 69.0 (62.0–75.0) 67.0 (61.0–74.0) 0.060a 65.0 (61.0–73.5) 68.0 (62.3–75.0)
BMI
 Continuous [kg/m2] 24.8 (22.8–27.8) 25.1 (22.5–28.6) 25.3 (23.1–28.5) 24.4 (22.2–27.4) 0.009a 24.3 (22.8–27.6) 24.7 (22.9–27.5)
 < 25 466 (51.2) 52 (49.0) 126 (46.2) 161 (55.5) 0.053b 30 (61.2) 97 (50.5)
 25–30 310 (34.1) 34 (32.1) 101 (37.0) 91 (31.4) 13 (26.5) 71 (37.0)
 > 30 134 (14.7) 20 (18.9) 46 (16.9) 38 (13.1) 6 (12.2) 24 (12.5)
Waist
 Continuous [cm] 77.0 (71.0–83.0) 77.0 (71.0–85.3) 78.0 (72.0–86.0) 76.0 (70.0–83.0) 0.008a 76.0 (69.5–83.0) 76.5 (71.0–82.0)
 < 81 603 (66.3) 64 (60.4) 171 (62.6) 197 (68.2) 0.063b 33 (67.3) 138 (71.9)
 81–85 116 (12.8) 16 (15.1) 30 (11.0) 43 (14.9) 7 (14.3) 20 (10.4)
 > 85 190 (20.9) 26 (24.5) 72 (26.4) 49 (16.9) 9 (18.4) 34 (17.7)
 Missing 1 0 0 1   0 0
Hip
 Continuous [cm] 97.0 (91.0–103.0) 98.0 (92.0–106.0) 97.0 (91.0–104.0) 96.0 (90.0–102.0) 0.014a 95.0 (90.0–103.0) 97.0 (92.0–102.8)
 Missing 1 0 0 1   0 0
Waist-hip ratio
 Continuous 0.79 (0.76–0.83) 0.79 (0.76–0.83) 0.80 (0.77–0.83) 0.79 (0.76–0.82) 0.095a 0.79 (0.75–0.84) 0.78 (0.75–0.82)
 ≤ 0.80 522 (57.4) 63 (59.4) 135 (49.5) 175 (60.6) 0.810b 27 (55.1) 122 (63.5)
 0.81–0.84 268 (29.5) 33 (31.1) 100 (36.6) 73 (25.3) 14 (28.6) 48 (25.0)
 ≥ 0.85 119 (13.1) 10 (9.4) 38 (13.9) 41 (14.2) 8 (16.3) 22 (11.5)
 Missing 1 0 0 1   0 0
Body fat percentage
 Continuous [%] 31.0 (27.8–34.0) 31.5 (28.0–35.0) 32.0 (28.0–35.0) 30.0 (27.0–33.8) 0.006a 30.0 (26.0–34.0) 31.0 (28.0–34.0)
 ≤ 24 83 (10.3) 9 (8.5) 20 (7.4) 46 (16.0) 0.007b 5 (10.2) 13 (6.8)
 25–31 395 (43.6) 44 (41.5) 114 (42.1) 121 (42.0) 23 (46.9) 93 (48.4)
 ≥ 32 418 (46.1) 53 (50.0) 137 (50.6) 121 (42.0) 21 (42.9) 86 (44.8)
 Missing 4 0 2 2   0 0
  1. aJonckheere-Terpstra test
  2. bLinear-by-linear association test. P value < 0.05 in bold