Table 3 Association of PD-L1 staining with clinicopathologic factors in triple-negative patients without neoadjuvant chemotherapy
| Â | TC | TCIC | IC | sTIL level | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Factors | Negative | Positive | Fisher | Negative | Positive | Fisher | Negative | Positive | Fisher | Low | High | Fisher |
N (%) | N (%) | P value | N (%) | N (%) | P value | N (%) | N (%) | P value | N (%) | N (%) | P value | |
Age | [N = 60] |  | [N = 59] |  | [N = 59] |  | [N = 59] |  | ||||
 < 50 years | 13 (87) | 2 (13) | 0.6339 | 11 (79) | 3 (21) | 0.5163 | 11 (79) | 3 (21) | 0.5163 | 6 (43) | 8 (57) | 0.5378 |
 ≥ 50 years | 41 (91) | 4 (9) |  | 30 (67) | 15 (33) |  | 30 (67) | 15 (33) |  | 15 (33) | 30 (67) |  |
Race/ethnicity | [N = 60] |  | [N = 59] |  | [N = 59] |  | [N = 59] |  | ||||
 Black | 13 (81) | 3 (19) | 0.3966 | 6 (38) | 10 (63) | 0.003 | 6 (38) | 10 (63) | 0.003 | 3 (19) | 13 (81) | 0.1211 |
 White+Latino | 40 (93) | 3 (7) |  | 34 (81) | 8 (19) |  | 34 (81) | 8 (19) |  | 17 (40) | 25 (60) |  |
 Others | 1 (100) | 0 (0) |  | 1 (100) | 0 (0) |  | 1 (100) | 0 (0) |  | 1 (100) | 0 (0) |  |
Histologic type | [N = 59] |  | [N = 58] |  | [N = 58] |  | [N = 58] |  | ||||
 IDC | 53 (90) | 6 (10) | NA | 40 (69) | 18 (31) | NA | 40 (69) | 18 (31) | NA | 20 (34) | 38 (66) | NA |
 Metaplastic | 0 (0) | 0 (0) |  | 0 (0) | 0 (0) |  | 0 (0) | 0 (0) |  | 0 (0) | 0 (0) |  |
Histologic grade | [N = 59] |  | [N = 58] |  | [N = 58] |  | [N = 58] |  | ||||
 2 | 11 (100) | 0 (0) | 0.582 | 8 (73) | 3 (27) | 1 | 8 (73) | 3 (27) | 1 | 5 (45) | 6 (55) | 0.4866 |
 3 | 42 (88) | 6 (13) |  | 32 (68) | 15 (32) |  | 32 (68) | 15 (32) |  | 15 (32) | 32 (68) |  |
sTIL level | [N = 59] |  | [N = 59] |  | [N = 59] |  | NA |  | ||||
 < 10% | 21 (100) | 0 (0) | 0.0796 | 21 (100) | 0 (0) | 0.0001 | 21 (100) | 0 (0) | 0.0001 |  |  |  |
 ≥ 10% | 32 (84) | 6 (16) |  | 20 (53) | 18 (47) |  | 20 (53) | 18 (47) |  |  |  |  |
Tumor size | [N = 59] |  | [N = 58] |  | [N = 58] |  | [N = 58] |  | ||||
 ≤ 2 cm | 31 (97) | 1 (3) | 0.14 | 25 (78) | 7 (22) | 0.1144 | 25 (78) | 7 (22) | 0.1144 | 14 (44) | 18 (56) | 0.2326 |
 > 2 to 5 cm | 19 (83) | 4 (17) |  | 14 (61) | 9 (39) |  | 14 (61) | 9 (39) |  | 6 (26) | 17 (74) |  |
 > 5 cm | 3 (75) | 1 (25) |  | 1 (33) | 2 (67) |  | 1 (33) | 2 (67) |  | 0 (0) | 3 (100) |  |
pN | [N = 59] |  | [N = 58] |  | [N = 58] |  | [N = 58] |  | ||||
 (y)pN0 | 37 (90) | 4 (10) | 0.7838 | 30 (73) | 11 (27) | 0.559 | 30 (73) | 11 (27) | 0.559 | 15 (37) | 26 (63) | 0.4834 |
 (y)pN1 | 11 (85) | 2 (15) |  | 7 (54) | 6 (46) |  | 7 (54) | 6 (46) |  | 3 (23) | 10 (77) |  |
 (y)pN2 | 3 (100) | 0 (0) |  | 2 (67) | 1 (33) |  | 2 (67) | 1 (33) |  | 1 (33) | 2 (67) |  |
 (y)pN3 | 2 (100) | 0 (0) |  | 1 (100) | 0 (0) |  | 1 (100) | 0 (0) |  | 1 (100) | 0 (0) |  |
pM | [N = 59] |  | [N = 58] |  | [N = 58] |  | [N = 58] |  | ||||
 0 | 51 (89) | 6 (11) | 1 | 39 (68) | 18 (32) | 1 | 39 (68) | 18 (32) | 1 | 20 (35) | 37 (65) | 1 |
 1 | 2 (100) | 0 (0) |  | 1 (100) | 0 (0) |  | 1 (100) | 0 (0) |  | 0 (0) | 1 (100) |  |
pStage | [N = 57] |  | [N = 56] |  | [N = 56] |  | [N = 56] |  | ||||
 I | 26 (93) | 2 (7) | 0.6264 | 22 (79) | 6 (21) | 0.3932 | 22 (79) | 6 (21) | 0.3932 | 12 (43) | 16 (57) | 0.437 |
 II | 19 (86) | 3 (14) |  | 13 (59) | 9 (41) |  | 13 (59) | 9 (41) |  | 5 (23) | 17 (77) |  |
 III | 4 (80) | 1 (20) |  | 3 (60) | 2 (40) |  | 3 (60) | 2 (40) |  | 2 (40) | 3 (60) |  |
 IV | 2 (100) | 0 (0) |  | 1 (100) | 0 (0) |  | 1 (100) | 0 (0) |  | 0 (0) | 1 (100) |  |