Fig. 5
From: Age-associated genes in human mammary gland drive human breast cancer progression
Knockdown of P4HA3 but not DYNLT3 significantly reduced malignancy of BT-474 cell in vivo. Comparison of tumor volume over time (a, d), final tumor weight (b, e), and total flux from luciferase activity in the lungs (c, f) between control and DYNLT3 or P4HA3 knockdown BT-474 cell-inoculated mice. Data are presented as the mean ± sem of ten tumors. Two-sample t tests were used to analyze the data.*P < 0.05; **P < 0.005