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Table 3 Multivariate Cox regression analysis on 5-year overall and disease-free survival

From: Clinical and functional significance of tumor/stromal ATR expression in breast cancer patients

ParameterOverall survivalDisease-free survival
Hazard ratio95% Cl†P*Hazard ratio95% Cl†P*
ATR (fibroblasts)14.7082.693–80.3320.00190.3690.151–0.9000.0285
Tumor size0.6650.084–5.2440.69851.0180.276–3.7590.9790
Age0.8780.802–0.9620.00511.0270.989–1.0670.1642
Stage95.6005.109–1788.6930.00230.4710.112–1.9750.3035
Grade0.8680.187–4.0300.85641.3630.647–2.8740.4155
HR_ Status ER(+ve)/Her2(−ve)8.9810.774–104.2590.07930.6490.283–1.4890.3079
HR_ Status ER(−ve)/Her2(+ve)31.4362.109–468.5440.01240.4120.102–1.6620.2096
HR_ Status ER(−ve)/Her2(−ve)30.2582.054–445.8030.01300.5920.161–2.2310.4445
ER_PR_Status ER(+ve)/PR(−ve)0.0740.003.009–1.7710.10800.7590.110–5.2540.7802
ER_PR_Status ER(+ve)/PR(+ve)0.8450.122–5.8370.86400.7260.169–3.1080.6655
ParameterOverall survivalDisease-free survival
 Hazard ratio95% Cl†P*Hazard ratio95% Cl†P*
ATR (epithelial cells)10.2421.745–60.1110.01000.8340.436–1.5980.5849
Tumor size0.0490.006–0.4250.00621.4590.402–5.3010.5659
Age0.8800.804–0.9620.00501.0280.989–1.0680.1637
Stage257.36013.853–4781.2700.00020.3340.084–1.3250.1188
Grade1.2050.266–5.4520.80831.3790.672–2.8320.3807
HR_ Status ER(+ve)/Her2(−ve)2.7310.382–19.5170.31660.6330.266–1.5050.3004
HR_ Status ER(−ve)/Her2(+ve)1.4560.146–14.4860.74880.6570.196–2.2070.4973
HR_ Status ER(−ve)/Her2(−ve)4.8170.459–50.5920.19010.6550.193–2.2250.4973
ER_PR_Status ER(+ve)/PR(−ve)0.9010.465–25.0580.92961.1870.207–6.8200.8474
ER_PR_Status ER(+ve)/PR(+ve)10.5110.671–164.6980.22751.0210.983–1.0610.2730