Table 3 Multivariate Cox regression analysis on 5-year overall and disease-free survival

Parameter

Hazard ratio

95% Cl†

P*

Hazard ratio

95% Cl†

P*

ATR (fibroblasts)

14.708

2.693–80.332

0.0019

0.369

0.151–0.900

0.0285

Tumor size

0.665

0.084–5.244

0.6985

1.018

0.276–3.759

0.9790

Age

0.878

0.802–0.962

0.0051

1.027

0.989–1.067

0.1642

Stage

95.600

5.109–1788.693

0.0023

0.471

0.112–1.975

0.3035

Grade

0.868

0.187–4.030

0.8564

1.363

0.647–2.874

0.4155

HR_ Status ER(+ve)/Her2(−ve)

8.981

0.774–104.259

0.0793

0.649

0.283–1.489

0.3079

HR_ Status ER(−ve)/Her2(+ve)

31.436

2.109–468.544

0.0124

0.412

0.102–1.662

0.2096

HR_ Status ER(−ve)/Her2(−ve)

30.258

2.054–445.803

0.0130

0.592

0.161–2.231

0.4445

ER_PR_Status ER(+ve)/PR(−ve)

0.074

0.003.009–1.771

0.1080

0.759

0.110–5.254

0.7802

ER_PR_Status ER(+ve)/PR(+ve)

0.845

0.122–5.837

0.8640

0.726

0.169–3.108

0.6655

Parameter

Hazard ratio

95% Cl†

P*

Hazard ratio

95% Cl†

P*

ATR (epithelial cells)

10.242

1.745–60.111

0.0100

0.834

0.436–1.598

0.5849

Tumor size

0.049

0.006–0.425

0.0062

1.459

0.402–5.301

0.5659

Age

0.880

0.804–0.962

0.0050

1.028

0.989–1.068

0.1637

Stage

257.360

13.853–4781.270

0.0002

0.334

0.084–1.325

0.1188

Grade

1.205

0.266–5.452

0.8083

1.379

0.672–2.832

0.3807

HR_ Status ER(+ve)/Her2(−ve)

2.731

0.382–19.517

0.3166

0.633

0.266–1.505

0.3004

HR_ Status ER(−ve)/Her2(+ve)

1.456

0.146–14.486

0.7488

0.657

0.196–2.207

0.4973

HR_ Status ER(−ve)/Her2(−ve)

4.817

0.459–50.592

0.1901

0.655

0.193–2.225

0.4973

ER_PR_Status ER(+ve)/PR(−ve)

0.901

0.465–25.058

0.9296

1.187

0.207–6.820

0.8474

ER_PR_Status ER(+ve)/PR(+ve)

10.511

0.671–164.698

0.2275

1.021

0.983–1.061

0.2730