Fig. 1
From: Modeling the natural history of ductal carcinoma in situ based on population data
Graphical representation of the DCIS model and its submodels. The figure depicts the states that are included in the model. The dotted arrow from the state preclinical screen-detectable DCIS to the state no breast cancer is included into the submodels where DCIS regression is allowed. The proportion of preclinical undetectable DCIS that progresses to preclinical screen-detectable DCIS can be 30%, 50%, or 80%. Different model assumptions on the natural history of DCIS are included for each submodel