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Fig. 2 | Breast Cancer Research

Fig. 2

From: Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer

Fig. 2

The effects of AIs, SERMs and fulvestrant on MCF7AC1 and MCF7LR cell growth in vitro. a Treatment with letrozole and exemestane in the presence of AND for 7 days. b Treatment with tamoxifen, Z-endoxifen, 4HT, and fulvestrant in the presence of AND for 7 days. c Treatments with aforementioned drugs mentioned in (b) in the absence of AND for 7 days. Growth was assessed by fixing the cells in 25% (v/v) glutaraldehyde followed by staining with 0.52% crystal violet in 25% methanol. Data is representative of six wells per treatment performed in biological triplicates and presented as mean ± SD. AND, androstenedione

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