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Fig. 6 | Breast Cancer Research

Fig. 6

From: Quantitative stain-free imaging and digital profiling of collagen structure reveal diverse survival of triple negative breast cancer patients

Fig. 6

Key collagen structural differences between the four groups of patients. a The distribution of the patients in the two-parameter space. b ATC area ratio, which is defined as the ratio between the aggregated collagen region area (the red area in Fig. 1d) and the total tissue area (the combination of the red and blue areas in Fig. 1d), is one of the key aspects of patient survival. This indicates the percentage of the given tissue area that is occupied by ATC. Patients with the best survival had significantly higher ATC area ratios compared with the other groups. c, d Differences in ATC CFD and DTC CFL in the four different groups, respectively. Error bars represent SE of the mean. *p < 0.05, **p < 0.0, ***p < 0.001, and >***p < 0.0001, with comparisons indicated by lines. p values calculated using one-way ANOVA and Tukey’s HSD test

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