TY - JOUR AU - Gallagher, Emily J. AU - Fei, Kezhen AU - Feldman, Sheldon M. AU - Port, Elisa AU - Friedman, Neil B. AU - Boolbol, Susan K. AU - Killelea, Brigid AU - Pilewskie, Melissa AU - Choi, Lydia AU - King, Tari AU - Nayak, Anupma AU - Franco, Rebeca AU - Cruz, Daliz AU - Antoniou, Irini M. AU - LeRoith, Derek AU - Bickell, Nina A. PY - 2020 DA - 2020/05/12 TI - Insulin resistance contributes to racial disparities in breast cancer prognosis in US women JO - Breast Cancer Research SP - 40 VL - 22 IS - 1 AB - Racial disparities in breast cancer survival between Black and White women persist across all stages of breast cancer. The metabolic syndrome (MetS) of insulin resistance disproportionately affects more Black than White women. It has not been discerned if insulin resistance mediates the link between race and poor prognosis in breast cancer. We aimed to determine whether insulin resistance mediates in part the association between race and breast cancer prognosis, and if insulin receptor (IR) and insulin-like growth factor receptor (IGF-1R) expression differs between tumors from Black and White women. SN - 1465-542X UR - https://doi.org/10.1186/s13058-020-01281-y DO - 10.1186/s13058-020-01281-y ID - Gallagher2020 ER -