Table 1 Upstream regulators identified by IPA having absolute Z-scores > 1 and predicted to be activated or inhibited in OB compared with NOB ADOL tissue samples
From: Investigation of the adolescent female breast transcriptome and the impact of obesity
Activated | Inhibited | |
|---|---|---|
Lipopolysaccharide | Forskolin | LY294002 |
MAFB | AKT1 | mir-21 |
IL10 | ESR1 | ADIPOQ |
CSF1 | IL6 | GATA6 |
IL10RA | CSF2 | IKZF1 |
TGM2 | TGFB1 | Immunoglobulin (Ig) |
Progesterone | Tretinoin | Â |
Dexamethasone | SPIB | Â |
USP22 | poly rI:rC-RNA | Â |
TCF4 | HGF | Â |
CCR2 | Tgf beta | Â |
Genistein | PGR | Â |
Tetradecanoylphorbol acetate | ERBB3 | Â |
IL4 | Â | Â |