Fig. 4
From: Investigation of the adolescent female breast transcriptome and the impact of obesity
Abundance of genes within the estrogen synthesis pathway a in breast tissue samples from b 62 ADOL and c 52 adult women (data downloaded from GTEx). Rows are individual samples, and columns are genes. Color intensity represents the normalized read counts corrected for the estimated proportion of adipocytes, scaled per kb of transcript length, and log2-transformed. ADOL samples are grouped by body type (non-overweight/obese (NOB), overweight/obese (OB); see y-axis). For each ADOL subgroup and for adults, samples are arranged vertically from those with the highest to lowest estimated adipocyte fraction. HSD17B, hydroxysteroid 17-beta dehydrogenase; AKR1B15, Aldo-Keto reductase family member B15; CYP19A1, aromatase; STS, steroid sulfatase; LIPE, hormone-sensitive lipase