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Fig. 2 | Breast Cancer Research

Fig. 2

From: Investigation of the adolescent female breast transcriptome and the impact of obesity

Fig. 2

Venn diagram showing the 500 most highly expressed genes in mammary tissue from the 62 ADOL (“adolescent”) subjects in the current studies, 52 adult women (from GTEx), and from post-pubertal/young adult mice, rats, and macaques. For each group, genes with the highest median expression were selected after excluding mitochondrial genes. Mouse data is from whole inguinal mammary glands from 6-week-old female C57Bl/6 mice (n = 4), rat data is from whole glands from female peri-pubertal (postnatal day 42, n = 5) or late pubertal (postnatal day 63, n = 5) Sprague-Dawley rats, and macaque data is from female cynomolgus macaques (n = 4) who underwent breast biopsies 7–12-months after menarche (see also Additional File 1: Table S5)

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