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Fig. 2 | Breast Cancer Research

Fig. 2

From: Cetuximab PET delineated changes in cellular distribution of EGFR upon dasatinib treatment in triple negative breast cancer

Fig. 2

[89Zr]Zr-cetuximab PET in EGFR differentially expressing TNBC xenografts. Mice bearing EGFR-high MDA-MB-231 (a) or MDA-MB-468 (b) and EGFR-low MDA-MB-453 (c) tumors imaged with [89Zr]Zr-cetuximab over time consistently displayed at least two-fold higher tumor uptake of the radiotracer in the high-expressing xenografts compared to the low EGFR-expressing tumor (d). Images are shown as maximum intensity projections. L = liver, B = bone. Tumors are identified by a white circle

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