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Table 1 Patient characteristics

From: TBCRC 002: a phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormone receptor-positive and HER2-negative breast cancer

Characteristic

Letrozole alone, n = 25

Letrozole/bevacizumab, n = 50

p value

Age (years)

 Median (range)

65 (50.4–86.3)

61.4 (50.4–81.9)

NSD

Race, n (%)

 White

20 (80)

42 (84)

NSD

 Black

3 (12)

6 (12)

NSD

 Hispanic

1 (4)

2 (4)

NSD

 Others

1—Asian (4)

–

 

Clinical tumor stage, n (%)

 IIA

9 (36)

16 (32)

NSD

 IIB

7 (28)

21 (42)

NSD

 IIIA

9 (36)

8 (16)

NSD

 IIIB

–

5 (10)

NSD

Nodal status, n (%)

 N0

9 (36)

21 (42)

NSD

 N+

16 (64)

29 (58)

NSD

Tumor type, n (%)

 Invasive ductal carcinoma

16 (64)

29 (58)

NSD

 Invasive lobular carcinoma

5 (20)

13* (26)

NSD

 Invasive mixed carcinoma

4 (16)

7 (14)

NSD

 Others

–

1—mucinous (2)

NSD

Histologic grade, n (%)

 Grade I

6 (24)

13 (26)

NSD

 Grade II

19 (76)

29 (58)

0.042

 Grade III

–

8 (16)

0.025

  1. *Includes one patient with concurrent separate invasive mucinous carcinoma
  2. NSD no significant difference